Course Offerings

Course Offerings 2016/2017

Course Schedule Fall, Winter, Spring

Graduate Chemistry Course Listing

Graduate Chemistry Course Regulations

Note that Guelph students register under the first number for each course (4 digits) while Waterloo students register with the second number listed (3 digits) where applicable.

Inor = Inorganic  Anl = Analytical  Bio = Biochemistry  Org = Organic  PhT = Physical/Theoretical  Poly = Polymer  GRes = General Research

Gue = Offered in Guelph  Wat = Offered in Waterloo
W/G = Offered in both Guelph and Waterloo  --- = Not Offered
ML = MainLink (EIT-2053/MACN-101) ml = minilink (C2-278/MACN-203)

Process for Ph.D. Comprehensive Examination

Ph.D. Oral Comprehensive Examination Process for Developing and Formatting

Process for M.Sc. and Ph.D. Thesis

University of Guelph M.Sc. and PhD. Thesis Timelines and Procedures

University of Waterloo M.Sc. and Ph.D. Thesis Evaluation and Preparation

Helpful Links

Tips for Preparing a Powerpoint Seminar

GWC2 Winter 2017 Classes Begin the week of 3 January 2017 see the course name link for specific dates

Area Course Name (click name for description)   S17 F17

Inor Chem 7100/710 Homogeneous and Heterogeneous Catalysis  (Outline)   --- ml
This course will provide an introduction and overview of the field of catalysis using heterogeneous metal/metal oxide and transition metal complexes focusing on general principles and reaction patterns of catalytically active transition metal centres and metal/metal oxide surfaces; mechanisms: kinetic and thermodynamic parameters and how to determine them; activation of small molecules such as hydrogen, carbon monoxide, carbon dioxide, methane, ethylene, propylene, ethylene oxide, etc.; large scale industrially relevant processes and their socio-economic importance. The ultimate objective of the course is to provide you with the know-how to understand (or at least make some educated guesses on) the mechanisms of any catalyzed reactions and have some insight into the principles of catalyst, reaction and process design. The course will be - as much as possible - conceptual in nature and thus should be suitable for students in any field of chemistry (inorganic, organic, physical and analytical) with 3rd year level undergraduate courses in inorganic and organic chemistry

F17 - ml - Schlaf, M 7:00-9:20pm
Inor Chem 7120/712 X-Ray Crystallography  (Outline)   --- ml
Introduction into chemical crystallography and X-ray diffraction (XRD) analysis. The course provides theoretical background for understanding the crystal structure analysis and data reported in the literature as well as hands-on training on the XRD equipment available. Part I: brief introduction into crystallography. Parts II & III: theory and practice of XRD analysis.

F17 - ml - Soldatov, T 7:00-9:20pm
Anl Chem 7200/720 Advanced Bioanalytical Chemistry  (Outline)   ml ---
Optical methods for matrix characterization (assays for total protein, DNA, RNA, carbohydrate, fatty acids). Introduction to enzymes: classification, nomenclature, specific activity. Review of enzyme kinetics (Michaelis-Menten and pseudo-Michaelis Menten kinetics, conditions for the assay of enzymes, substrates, activators and inhibitors). Enzyme assays, including high-throughput screening (HTS) methods. Immobilization of enzymes: methods including adsorption, entrapment, crosslinking, covalent immobilization and encapsulation; effect of immobilization on kinetics, pH dependence and stability. Immobilized enzyme reactor (IMER) configurations and applications, including lab-on-a-chip devices. Introduction to antibodies: structure, types of natural immunoglobulins, monoclonal and engineered antibodies, characterization of antibody-antigen binding reactions. Immunoassays based on secondary Ab:Ag reactions (including blood typing and other agglutination tests, precipitin tests, single radial immunodiffusion). Quantitative immunoassays based on labels: classification as heterogeneous or homogeneous, label types including radiolabels, fluorophores, enzymes, luminescent and others. Nucleic acid assays and arrays based on immunoassay principles. Biosensors: integration of recognition agents with measurement devices; characterization methods; examples of devices for in vitro and in vivo measurements. Separation methods: zone electrophoresis and isoelectric focussing on gels and in capillaries, immunoassays in capillaries; DNA sequencing; 2D electrophoresis; staining and activity-based detection of separated analytes; chromatographic methods for biomacromolecules including gel filtration and affinity methods; lab-on-a-chip devices incorporating separation and detection stages. Validation of bioanalytical methods and devices.

S17 - ml - Mikkelsen, M,Th 1:00-3:20pm Scheduled from 1 May to 12 June
Anl Chem 7270/727 Separations  (Outline)   --- ML
Material to be covered will be drawn from these topics: separations in engineering and analytical processes; unit processes; sample preparation techniques; membrane separations; chromatographic techniques; gas; liquid; supercritical fluid chromatography; physiochemical application of chromatography; electrophoresis techniques: gel, capillary, moving boundary, zone, isotachophoresis; capillary separations; detection methods; multidimensional separations; and flow field fractionation.

F17 - ML - Pawliszyn, Th 7:00-9:20pm
Bio Chem 7310/731 Structure and Function of Nucleic Acids  (Outline)   --- ML
This course covers advanced topics in structure and function of nucleic acids. Among the topics discussed are: Basic principles of DNA and RNA chemistry, biochemistry and structure; Analytical methods used for the study of nucleic acids; Biochemical methods for the study of nucleic acids including SELEX; Structure determination of nucleic acids by NMR spectroscopy; Nucleic acids in medical applications; Nucleic acid nanotechnology; and Nucleic acids in molecular biology.

F17 - ML - Dieckmann, TTh 1:00-2:20pm (held with an undergraduate course)
Bio Chem 7310/731 The Polysaccharides  (Outline)   --- ML
This course covers the physical and immunogenic aspects of plant, microbial and mammalian polysaccharides, and their application in therapeutics and vaccines. The main body of the course will be formed by in-class oral presentations based on recent literature provided by the instructor. Students and instructor will deliver in-depth analyses of articles describing the latest science in the fields of polysaccharide structure, biology, immunology and experimental methodology. The midterm and final exam will consist of a take-home problem set assignment.

F17 - ML - Monteiro, W 7:00-9:20pm
Bio Chem 7370/737 Enzymes  (Outline)   ml ---
This graduate course will address the underlying principles of enzymatic catalysis (with examples) along with discussion of techniques that are applied to this area. This course focuses on the protein itself and how its structure contributes to catalysis. Subtopics will include protein dynamics, electrostatic potential, active-site geometry and transition state stabilization among other factors that contribute to enzyme catalysis and substrate selectivity. The chemical mechanism of example enzymes will also be discussed. A survey of the chemical reaction mechanisms that are involved for the six Enzyme Commission (EC) classes of enzymes as well as some of the techniques (kinetic isotope effects, PIX experiments, enzyme inhibitors, for example) used to aid in studying how a particular enzyme catalyzes a reaction will be presented. If time permits, applications of select enzymes may be discussed.

S17 - ml - Honek, WF 2:00-4:20pm Scheduled from 3 May to 16 June 2017
PhT Chem 7400/740 Computational Chemistry  (Outline)   --- Wat
This course will provide a practical guide to quantum chemical calculations. The course will be held mainly in a computer lab setting, with students performing calculations under guidance of the instructor. In addition the lecture material will cover main topics in computational chemistry. A major component of the course is the computational research project. Each student in the class follows an individual trajectory, based on their interests and their choice of research project.

F17 - Wat - Nooijen, B1 370 TTh 11:30-12:50am (combined with undergraduate course)
PhT Chem 7500/750 Nanotechniques  (Outline)   ml ---
Introduction to basic principles of the common tools used for materials research and nanosciences; hands-on training of sample preparation, use and operation as well as data analysis involving common nanotool instrument systems, including light microscopy, scanning electron microscopy and related techniques, X-ray diffraction, optical spectroscopy and/or electron spectroscopy, and atomic force microscopy. This course is designed for junior students who have had minimal experience in the techniques covered in the syllabus.

S17 - ml - Leung, W 10:30am-12:20pm and W 01:30-05:20pm C2 081 Waterloo Scheduled from 3 May to 14 June 2017
PhT Chem 7500/750 Bioelectronics  (Outline)   --- ml
This course covers many advanced topics in the principle, fabrication, and applications of bioelectronics involving nanotechnology. The students will be introduced to the fundamental building blocks of bioelectronics, strategies for fabrication/organization of micro/nanostructures, and design/characterization of the bio-interfaces. Frontier research in the field of bioelectronics and applications (e.g. biosensors, implantables, cell culture analog, biological computers), especially advancements enabled by nanotechnology, will be reviewed at the conclusion.

F17 - ml - Tang, Th 7:00-9:20pm
PhT Chem 7500/ Nano 701A & 702A Nanoscale Surfaces/Interfaces and Spectro-microscopy,   --- ml
To be provided

F17 - ml - Radovanovic, W 7:00-9:20pm
Org Chem 7600/760 Advanced Carbohydrate Chemistry  (Outline)   --- Gue
Topics covered in this course include: structure of monosaccharides: configurations, ring size, conformations, mutarotation, anomeric effect; Biological relevance of carbohydrates: disaccharides, oligosaccharides, polysaccharides, biosynthesis and synthetic biochemical tools; Carbohydrate Synthetic Chemistry: A. Protecting groups in carbohydrate chemistry and synthetic strategies: Alkyls, acyls, silyls, acetals and ketals, selectivity etc… The daunting task of multi-step carbohydrate synthesis! B.The glycosylation reaction: when titans collide, the challenge of carbohydrate chemistry. Principle of glycosylation, armed-disarmed glycosyl donors, participating groups, anomeric effect and kinetic anomeric effect, glycosylation methods: Fisher, Koenigs-Knorr, Helfrich, thioglycosides, trichloroacetimidates and many others; and NMR of carbohydrates: chemical shifts, coupling constants, 1D, 2D (real life examples).

F17 - Gue - Auzanneau, MCKN 225 MWF 8:30-9:20am (held with an undergraduate course)
Org Chem 7600/760 Synthetic Methods in Organic and Organometallic Chemistry  (Outline)   --- ML
This course will familiarize students with the basics of main group and transition metal chemistry (formalisms) and provide a practical introduction to the mechanisms of organometallic reactions. The importance of main group and transition metal-catalyzed bond-forming processes in organic synthesis will be illustrated with examples of applications in the synthesis of natural products.

F17 - ML - Fillion, T 7:00-9:20pm
Poly Chem 7700/770 Principles of Polymer Science   --- Wat
To be provided.

F17 - Wat - Gauthier, RCH 204 TTh 8:30-9:50am (combined with undergraduate course)
Poly Chem 7730/773 Fluorescence: Principles, Theory and Applications to the Characterization of Macromolecules and Supramolecular Assemblies   --- Wat
This course will begin with a thorough description of the fundamentals of fluorescence. The Jablonski diagram and its implications to the absorption and fluorescence spectra of dyes will be reviewed. Based on this knowledge, the parts constituting a steady-state fluorometer will be introduced and their operation will be described to obtain artefact-free fluorescence spectra. In particular, the different geometries (right angle and front-face geometries) that are available to the experimentalist to acquire fluorescence spectra will be presented as well as the justification for their use based on whether the fluorescence experiment is conducted with a low or high dye concentration. The time-resolved fluorometer which is used to acquire fluorescence decays will be presented along with the information that an experimentalist is expected to retrieve from conducting such experiments. Mastering the use of a steady-state and time-resolved fluorometer enables the experimentalist to apply a number of well-established experimental techniques to probe matter at the molecular level. These techniques will be described in details.

F17 - Wat - Duhamel, C2 361 M 7:00-9:20pm
GRes Chem 7940/794 M.Sc. Seminar (G) / M.Sc. Seminar (W)  (Outline)   W/G W/G
A written literature review and research proposal on the chosen thesis topic will be presented and defended in a 30-minute public seminar. This requirement is to be completed by all M.Sc students completing their degree by thesis, within two terms of entering the program.

S17 - Gue - Monteiro
F17 - Gue - Monteiro
S17 - Wat - Gauthier
F17 - Wat - Gauthier
GRes Ph.D. Seminar (G) / Ph.D. Seminar (W)  (Outline)   W/G W/G
A public seminar on the chosen thesis topic to be given by all Ph.D. students in the regular program in the second term of entering the program. For Co-op Ph.D. students, this seminar is to be presented within six terms of their return from work year.

S17 - Gue - Monteiro
F17 - Gue - Monteiro
S17 - Wat - Supervisor
F17 - Wat - Supervisor
GRes Comprehensive Examination (G) / Comprehensive Examination (W)  (Outline)   W/G W/G
Ph.D. students are required to take an oral examination in their major field. The specific content and format are specified by a Centre Examining Committee. The examination must be first attempted no later than 6 weeks after presenting their 795 Ph.D. seminar. For Co-op Ph.D. students, the examination must be first attempted no later than 4 months after their return from work year.

S17 - W/G - Managed through the GWC2 Director's office
F17 - W/G - Managed through the GWC2 Director's office
GRes M.Sc. Research Project (G) / M.Sc. Research Project (W)  (Outline)   W/G W/G
A study of a selected topic in chemistry or biochemistry, by students in the part-time course-based M.Sc. option. The project must be an experimental one, completed by working for one term in the laboratory of a (GWC)2 faculty member. A written report is required, and a seminar based on the content of the report will be presented.

S17 - W/G - See your graduate officer
F17 - W/G - See your graduate officer
GRes M.Sc. Thesis (G) / M.Sc. Thesis (W)   W/G W/G
M.Sc. Thesis and Defense

S17 - W/G - See your graduate officer
F17 - W/G - See your graduate officer
GRes Ph.D. Thesis (G) / Ph.D. Thesis (W)   W/G W/G
Ph.D. Thesis and Defense

S17 - W/G - See your graduate officer
F17 - W/G - See your graduate officer
Two Great Universities - One Great Graduate Program
Guelph-Waterloo Centre for Graduate Work in Chemistry and Biochemistry
Guelph/Waterloo, Ontario, Canada
519-824-4120 x53848
Fax: 519-766-1499